Aceclofenac 100 mg, Tolperisone HCl 150 mg & Paracetamol 325 mg Tablets

Description

Aceclofenac 100 mg, Tolperisone HCl 150 mg & Paracetamol 325 mg – Aceclofenac 100 mg, Tolperisone HCl 150 mg & Paracetamol 325 mg Tablets are a combination of medicines that contain pain relievers and muscle relaxants and are used to treat pain associated with muscle spasms. These tablets improve muscle movement and relieve pain and discomfort caused by the muscle spasm. Aceclofenac 100 mg, Tolperisone HCl 150 mg & Paracetamol 325 mg Tablets contains Aceclofenac, Tolperisone is a muscle relaxant and Paracetamol is a pain killer. 

Aceclofenac 100 mg, Tolperisone HCl 150 mg & Paracetamol 325 mg Tablets are available in the market at Saphnix Lifesciences. Tolperisone in these tablets works on the spinal cord and brain centers to relieve muscle stiffness without decreasing strength. Aceclofenac and Paracetamol in these tablets block prostaglandins that cause pain and swelling.

Uses of Aceclofenac 100 mg, Tolperisone HCl 150 mg & Paracetamol 325 mg

Aceclofenac 100 mg, Tolperisone HCl 150 mg, and Paracetamol 325 mg are combined in some formulations to treat various conditions. Here’s a breakdown of their uses:

• It reduces inflammation by inhibiting prostaglandin synthesis, which helps in relieving pain and swelling.
• Acts as a painkiller to alleviate mild to moderate pain. It may also provide mild pain relief associated with muscle spasms.
• It acts directly on the central nervous system to relieve muscle stiffness and spasms without causing sedation.

Mechanism of Aceclofenac 100 mg, Tolperisone HCl 150 mg & Paracetamol 325 mg

Here’s a detailed look at the mechanisms of action for Aceclofenac, Tolperisone HCl, and Paracetamol:

• Aceclofenac (100 mg):

1. 1. • Mechanism: Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that inhibits the enzyme cyclooxygenase (COX), specifically COX-2 more than COX-1.
      • Function: By inhibiting COX enzymes, Aceclofenac reduces the synthesis of prostaglandins from arachidonic acid. Prostaglandins are chemical mediators in inflammation, pain, and fever pathways. By reducing their production, Aceclofenac alleviates pain, inflammation, and swelling associated with arthritis.

• Tolperisone HCl (150 mg):

1. 1. • Mechanism: Tolperisone HCl is a centrally-acting muscle relaxant.
      • Function: It exerts its effects by modulating calcium ion influx through voltage-gated channels in neurons of the central nervous system. This action reduces muscle stiffness and spasms without causing significant sedation, making it suitable for treating musculoskeletal disorders and conditions involving muscle spasms.

• Paracetamol (325 mg):

1. • Mechanism: Paracetamol’s exact mechanism of action is not fully understood but is believed to involve inhibition of prostaglandin synthesis in the central nervous system (CNS).
   • Function: It mainly acts as an analgesic (pain reliever) and antipyretic (fever reducer). Paracetamol is thought to exert its effects by inhibiting COX enzymes in the CNS, thus reducing pain perception and lowering fever.

Combined Mechanism:

• The combination of Aceclofenac, Tolperisone HCl, and Paracetamol in a single formulation provides a synergistic effect:
  • Pain Relief: Aceclofenac and Paracetamol both act to relieve pain through different mechanisms (inhibition of peripheral and central prostaglandin synthesis, respectively).
  • Inflammation Control: Aceclofenac targets inflammation locally at the site of injury or disease.
  • Muscle Relaxation: Tolperisone HCl acts centrally to relax muscles, reducing spasms and associated pain.
  • Fever Reduction: Paracetamol helps in lowering fever through its antipyretic action.

Side Effects 

There are mild to moderate side effects of Aceclofenac 100 mg, Tolperisone HCl 150 mg & Paracetamol 325 mg Tablets that resolve over time. Side effects are mentioned as follows:

• Nausea
• Vomiting
• Stomach pain
• Diarrhea
• Indigestion
• Loss of appetite
• Heartburn

Note: Immediately inform your doctor in case the side effects from these tablets persist or get severe with time. 

Precautions

1. Avoid alcohol consumption as it may increase the chances of stomach bleeding. 
2. Aceclofenac, Tolperisone & Paracetamol Tablets are not safe during pregnancy and breastfeeding, hence, do not take them without a doctor’s consultation. 
3. Store the tablets in a cool and dry place away from direct sunlight. 
4. Also, tell your doctor about your medical history and other medications you are currently taking.
5. Take this medication with food to avoid getting an upset stomach.